BCR/ABL1 FISH
t(9;22) FISH
CML
709.21
Includes culture processing charge.
2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI
4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze.
Peripheral blood is suitable if there are >10% blasts in circulation.
Ambient on day of collection. Refrigerate overnight or weekend then send ambient
Cytogenetics
Urgent < 5 days, Non-urgent 18 days
Flourescence in situ hybridisation (FISH) with BCR and ABL1 specific probes to identify and characterise the t(9;22)(q34;q11.2) Philadelphia chromosome rearrangement.
Refer to report
1 ml BMA in RPMI or 1.0 ml Heparin (Dark green) whole blood sterile > 10% blasts
FBCR_ABL
$FBCR_ABL
