BCL6 breakapart (FISH)
3q27 BCL6 del/rearr
Includes culture processing charge.
2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI
4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze.
Blood Samples are preferred for CLL and ?LPN patients with peripheral lymphocytosis.
For other disorders, peripheral blood is suitable if there are >10% blasts in circulation.
Ambient on day of collection. Refrigerate overnight or weekend then send ambient.
Urgent 5 days, Non Urgent 18 days
Flourescence in situ hybridisation (FISH) with BCL6 specific probes. to identify and characterise 3q27 chromosome rearrangements.
Refer to report
Detect and characterise 3q27 chromosome rearrangements.
1 ml Bone marrow aspirate in RPMI.