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Laboratory Test Reference Guide

Laboratory Information

Test Name

BCL6 breakapart (FISH)


3q27 BCL6 del/rearr

External Price (excl. GST)


Price Comment

Includes culture processing charge.

Specimen Collection

Specimen Collection and Transport Protocols

2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI

4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze. 

Blood Samples are preferred for CLL  and ?LPN patients with peripheral lymphocytosis. 

For other disorders, peripheral blood is suitable if there are >10% blasts in circulation. 

Sample Delivery to Lab

Ambient on day of collection. Refrigerate overnight or weekend then send ambient.

Test Information



Laboratory Turnaround Time

Urgent 5 days, Non Urgent 18 days


Flourescence in situ hybridisation (FISH) with BCL6 specific probes. to identify and characterise 3q27 chromosome rearrangements.

Uncertainty of measurement

Refer to report

Diagnostic Use Or Instructions

Detect and characterise 3q27 chromosome rearrangements.

Minimum Volume

1 ml Bone marrow aspirate in RPMI.

Electronic Information

Registration Code


HL7 mapping code