Vancomycin
21
The trough level is the critical one. Most problems are due to under dosing. The recommended sample is one collected within 1 hour before the next scheduled dose (or at steady state, if a continuous infusion is used). In situations where Vd or clearance are very uncertain, an AUC may be estimated from peak and trough levels. Samples are registered as either Pre dose (trough) or Post dose (random). It is the responsibility of the clinician to determine when the sample was collected relative to the dosing.
Heparin (light green), SST (gold), "T-" labs SST (gold). Plain (red) for samples referred from Rural Hospitals
0.4 mL Heparin (light green) or Plain(red).
Biochemistry
Mon - Sun, 24hrs
3 hrs
Cobas Pro Online
ug/mL
Trough levels should be 15 - 20 ug/mL for treating S. aureus.
Refer to Vancomycin Monitoring in Waikato DHB Micro Guide (under intranet applications) for further information and guidance regarding dose adjustment.
15%
0.2 mL plasma or serum.
VPRE, VRAND
$VPRE, $VRAND
