Valproate
Valproic acid, Epilim, Sodium Valproate
17.5
Heparin (light green), SST (gold), "T-" labs SST (gold), Plain (red) for samples referred from Rural Hospitals
Sample should be collected at least 8 hours after the last dose.
0.4 mL Heparin (light green) or Plain(red).
Biochemistry
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umol/L
The minimum therapeutic level is considered to be 350 umol/L and toxicity may be teen at levels > 700 umol/L. However, there is a poor correlation between serum levels and effectiveness of Valproate. The dose can be adjusted on the basis of effectiveness balanced against side effects.
Routine measurement of Valproate is not clinically useful. Indications for testing include:
1) Assessing toxicity
2) Assessing compliance
3) Following adjustment of the dose
4) Adding or withdrawing drugs with potential drug – drug interactions.
10%
0.2 mL plasma or serum.
VALP
$VALP
14946-8
