Laboratory Test Reference Guide

Laboratory Information

Test Name

TP53 FISH

Synonyms

del17p FISH

External Price (excl. GST)

709.21

Price Comment

Includes culture processing charge.

Specimen Collection

Specimen Collection and Transport Protocols

2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI

4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze. 

For TP53 mutation 4 ml EDTA (Purple) Whole blood sterile. Do not centrifuge or freeze.

Blood Samples are preferred for CLL  and ?LPN patients with peripheral lymphocytosis. 

For other disorders, peripheral blood is suitable if there are >10% blasts in circulation. 

Test Information

Department

Cytogenetics

Laboratory Turnaround Time

Urgent 5 days, Non-urgent 18 days

Method

Flourescence in situ hybridisation (FISH) with TP53 specific probes.

Uncertainty of measurement

Refer to report

Diagnostic Use Or Instructions

Detect and characterise TP53 (17p13) chromosome deletions.

Electronic Information

Registration Code

FTP53

HL7 mapping code

$FTP53