Thyroid Antibodies
microsomal antibodies
TPO antibodies
thyroglobulin antibodies
thyroid peroxidase antibodies
5 mL blood in gold tube or 0.5mL separated serum.
Biochemistry
Mon - Fri, 0800 - 1630 excl. Public Holidays
7 days.
Electrochemiluminescent Immunoassay
IU/mL
Thyroid Peroxidase antibodies <35 IU/mL
Anti-TPO <15%
Previously, Anti-TG antibodies and anti-TPO antibodies were measured. During March 2017, Anti-TG antibodies were discontinued.
Anti-TPO antibodies offer better performance than anti-TG antibodies for detecting the presence of auto-immune thyroid disease. The only indication for measuring anti-TG antibodies is to check for assay interference when Thyroglobulin (TG) is measured. Thyroglobulin is mainly used as a tumour marker in the follow-up of patients with thyroid cancer. Anti-TG antibodies are present in about 25% of patients with thyroid cancer and can interfere with the TG assay, causing a falsely low result. A specific assay (Roche), validated for TG measurement is required. Anti-TG results are assay specific, with large variation seen between assays, which may cause confusion with interpretation of the TG result.
THYGR
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