Laboratory Test Reference Guide

Laboratory Information

Test Name

Myeloma FISH panel

Synonyms

Multiple Myeloma

Specimen Collection

Adult Specimen

2 ml Bone marrow aspirate in RPMI

Pre Testing Requirements

>10% plasma cells in BMA

Paediatric Specimen

Test Information

Department

Cytogenetics

Laboratory Turnaround Time

Urgent 5 days, Non-urgent 18 days

Method

Flourescence in situ hybridisation (FISH) on CD138 isolated plasma cells with probes for 1p/1q gain or loss, IGH/FGFR3 t(4;14) rearrangement and TP53 deletions with reflex testing to IGH/CCND1 rearrangement also available

Uncertainty of measurement

Refer to report

Diagnostic Use Or Instructions

Haematologist approval required.

Electronic Information

Registration Code

FMMPAN

HL7 mapping code

$FMMPAN