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Laboratory Test Reference Guide

Laboratory Information

Test Name

Myeloma FISH panel

Synonyms

Multiple Myeloma

Specimen Collection

Pre Testing Requirements

>10% plasma cells in BMA

Adult Specimen

2 ml Bone marrow aspirate in RPMI

Paediatric Specimen

Sample Delivery to Lab

Ambient on day of collection. Refrigerate overnight or weekend then send ambient.

Test Information

Department

Cytogenetics

Laboratory Turnaround Time

Urgent 5 days, Non-urgent 18 days

Method

Flourescence in situ hybridisation (FISH) on CD138 isolated plasma cells with probes for 1p/1q gain or loss, IGH/FGFR3 t(4;14) rearrangement and TP53 deletions with reflex testing to IGH/CCND1 rearrangement also available

Uncertainty of measurement

Refer to report

Diagnostic Use Or Instructions

Haematologist approval required.

Electronic Information

Registration Code

FMMPAN

HL7 mapping code

$FMMPAN