Infectious mononucleosis (screen)
Glandular fever screen
Monospot
7
5 mL blood Plain tube (red) or EDTA tube (purple).
A CBC with differential is an essential component of this test. Please ensure one is ordered at time of collection.
500uL serum or plasma
Send at 4°C
Haematology
Mon - Sun, 24hrs
2 hrs
Infectious mononucleosis (IM) is an acute herpes viral infection caused by the Epstein-Barr virus (EBV). The peak incidence is between 15 and 19 years of age.
A positive IM screen test indicates the presence of the heterophile antibody and is consistent with Infectious Mononucleosis (Glandular Fever). During the acute phase of the illness, IM heterophile antibodies (primarily of the IgM class) appear in 80-90% of cases. IM antibodies are usually demonstrable 1-12 weeks after the onset of the illness, but have been shown to persist for up to a year.A review of the blood film should also reveal reactive lymphocytes which are variable in size and appearance and show deeply basophilic cytoplasm (Infectious Mononucleosis Cells).The results of the IM screen test must be part of other clinical and diagnostic results. Other disease states can be confused with or mimic infectious mononucleosis and must be differentiated from IM.
1 mL blood Plain tube (red) or EDTA tube (purple).
IMS
$IMS
31418-7