HLA DQ2/DQ8
Coeliac gene testing
DQ2
DQ8
52.16
Purple (EDTA) tube
Molecular samples must be dedicated tube i.e. do not share with haematology
Paediatric Purple (EDTA) tube
1mL Whole blood
Chilled
Molecular Biology
Batched fortnightly
PCR
NOT detected / DETECTED
Coeliac disease is associated with HLA DQ2 and/or HLA DQ8. The presence of at least one of these alleles means that coeliac disease cannot be excluded. However only a minority of people with these alleles have coeliac disease.
If HLA-DQ2 and DQ8 are not detected, Coeliac disease is highly unlikely. In <1% of cases, coeliac disease may occur in the absence of the alleles tested. (Dr Marianne Empson, Immunopathologist)
Alleles detected by this PCR: HLA-DQB*02 and HLA-DQB*03:02
