Laboratory Test Reference Guide

Laboratory Information

Test Name

D12Z3 FISH

Synonyms

FISH
Fluorescent in situ hybridization

External Price (excl. GST)

709.21

Price Comment

Includes culture processing charge.

Specimen Collection

Specimen Collection and Transport Protocols

2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI

4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze. 

Blood Samples are preferred for CLL  and ?LPN patients with peripheral lymphocytosis. 

For other disorders, peripheral blood is suitable if there are >10% blasts in circulation. 

Test Information

Department

Cytogenetics

Laboratory Turnaround Time

Urgent < 5 days, Non-urgent 18 days

Method

Flourescence in situ hybridisation (FISH) with D12Z3 specific probes. to identify and characterise chromosome 12 centromere anomalies. Lymphoproliferative disorders.

Uncertainty of measurement

Refer to report

Diagnostic Use Or Instructions

Detect and characterise chromosome 12 centromere anomalies in Lymphoproliferative disorders.

CLL panel also available.

Minimum Volume

 

Electronic Information

Registration Code

FD12Z3

HL7 mapping code

$FD12Z3