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Laboratory Test Reference Guide

Laboratory Information

Test Name



Cyclic Citrullinated Peptide Antibodies

External Price (excl. GST)



Specimen Collection

Adult Specimen

Gold or Red tube

Paediatric Specimen

Paediatric Gold or Red tube

Instructions for Referral to Waikato Lab

Aliquot instructions

300uL Serum

Aliquot Transport


Test Information



Laboratory Turnaround Time

Batched weekly


Bioflash (CLIA)

Unit of measurement


Reference interval

<20 CU

Uncertainty of measurement


Diagnostic Use Or Instructions

Think carefully before repeating rheumatology and immunology tests. Do not repeat immunology tests in known positive patients (for example ANA, RF) on every admission.

If the test is strongly positive there is little benefit in repeating it ever. If a weak positive it could be repeated at 6 months. If negative we might repeat again at 6 months if we felt RA was likely.

Once decided if positive or negative for a patient there is no reason to repeat the test unless there is some major clinical change.

  • Do not request anti-CCP unless there is a clinical suspicion of an inflammatory polyarthritis that might be rheumatoid arthritis. In an inflammatory mono-arthropathy only request anti-CCP if other causes such as infection, gout and reactive arthritis are considered to be unlikely.
  • Do not repeat anti-CCP or Rheumatoid Factor without careful consideration.