Cortisol
Synacthen stimulation test
13.53
Heparin (light green), SST (gold)
0.4ml Heparin (light green) or Plain(red).
Biochemistry
Mon - Sun, 24hrs
3 hrs
Cobas Pro ECLIA
nmol/L
0600 – 1000 hrs : 170 - 500 nmol/L
Samples collected outside this period will be reported with the following comment:
“The cortisol reference interval is not well defined for the time of collection.”
When cortisol is < 100 on a sample collected between 0600 – 1000:
“A cortisol result < 100 nmol/L is suspicious of adrenal insufficiency. Consider an endocrine opinion.”
When cortisol is > 300 on a sample collected between 0600 – 1000:
“In the absence of acute illness, this cortisol result suggests adrenal insufficiency is unlikely.”
Following Synacthen Stimulation (0.25 mg IM)
30 minutes:” A result ≥ 400 nmol/L suggests adequate adrenal reserve”
60 minutes:” A result ≥ 460 nmol/L suggests adequate adrenal reserve”
Following Dexamethasone Suppression (1mg oral given at 2300 hr) -
0800 hrs the cut-off for “normal suppression” is 50 nmol/L or below
(Implemented by Dr S du Toit on 21 September 2015 following discussion with Waikato Endocrinologists)
10%
Please note that the lab neither supplies the synacthen nor performs the test. Please contact the Medical Day Care Unit or Pharmacy for further assistance.
0.2 mL plasma or serum.
CORT
$CORT
14675-3
