CLL panel FISH
Includes culture processing charge.
4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze.
2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI
For TP53 mutation 4 ml EDTA (Purple) Whole blood sterile. Do not centrifuge or freeze.
Blood Samples are preferred for CLL and ?LPN patients with peripheral lymphocytosis.
For other disorders, peripheral blood is suitable if there are >10% blasts in circulation.
Ambient on day of collection. Refrigerate overnight or weekend then send ambient.
Urgent 5 days, Non-urgent 18 days
Flourescence in situ hybridisation (FISH) probe CLL panel.
Refer to report
Detects 11q22.3 ATM deletion,Trisomy 12 D12Z3, 13q14 D13S319 deletion and 17p13 TP53 deletion associated with CLL.
Probes can also be ordered individually for other Lymphoproliferative neoplasms (LPN)