Laboratory Test Reference Guide

Laboratory Information

Test Name

Acetone

External Price (excl. GST)

45.21

Specimen Collection

Adult Specimen

Whole Blood - EDTA (Lavender Tube).

Pre Testing Requirements

Collect specimen at end of shift or exposure.
When collecting the sample the tube should be filled to near the top to prevent loss of acetone by volatilization into the headspace.

Specimen Collection and Transport Protocols

Preferred Sample Volume: 4 ml.

Do not swab the venepuncture site with alcohol.

Do not use SST gel tubes.

Instructions for Referral to Waikato Lab

Aliquot instructions

Minimal head space.

Test Information

Department

Sendaway - Biochemistry

Test Availability

Referred to external laboratory.

Laboratory Turnaround Time

7 days

Method

Gas Chromatography Headspace

Unit of measurement

mmol/L

Reference interval

Toxic levels for acetone are not well defined. Levels up to 15 mmol/L has been reported in patients with ketoacidosis.

Ingested isopropanol is metabolised to acetone therefore isopropanol toxicity does not cause a metabolic acidosis; the isopropanol level is usually higher than the acetone level.  In patients with  ketoacidosis, acetone is metabolised to isopropanol and acetone levels are usually higher than isopropanol level.

 

Referred Out