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Laboratory Test Reference Guide

Laboratory Information

Test Name

KMT2A breakapart FISH

Synonyms

11q23 FISH
MLL

External Price (excl. GST)

709.21

Price Comment

Includes culture processing charge.

Specimen Collection

Specimen Collection and Transport Protocols

2 - 10 ml bone marrow aspirate in RPMI, Bone marrow trephine in RPMI

4 ml Heparin (Dark green) Whole blood sterile. Do not centrifuge or freeze. 

Blood Samples are preferred for CLL  and ?LPN patients with peripheral lymphocytosis. 

For other disorders, peripheral blood is suitable if there are >10% blasts in circulation. 

Sample Delivery to Lab

Ambient on day of collection. Refrigerate overnight or weekend then send ambient.

Test Information

Department

Cytogenetics

Laboratory Turnaround Time

Urgent 5 days, Non-urgent 18 days

Method

Flourescence in situ hybridisation (FISH) with KMT2A specific probe.

Uncertainty of measurement

Refer to report

Diagnostic Use Or Instructions

Detect and characterise 11q23 chromosome rearrangements and amplifications in haematological neoplasms.

Electronic Information

Registration Code

FMLL

HL7 mapping code

$FMLL