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Laboratory Test Reference Guide

Laboratory Information

Test Name

Hepatitis C serology

Synonyms

Hepatitis C antibody

External Price (excl. GST)

23.32

Specimen Collection

Adult Specimen

Gold or Red tube

Paediatric Specimen

Paediatric Gold or Red tube

Instructions for Referral to Waikato Lab

Aliquot instructions

500uL

Aliquot Transport

Chilled

Test Information

Department

Virology

Test Availability

Mon - Fri, 0800 - 1630 excl. Public Holidays

Laboratory Turnaround Time

24-48 hours

Method

Cobas Pro

Diagnostic Use Or Instructions

  • Anti-HCV antibody is present in almost all those infected with HCV, but depending on the age and sex at acquisition, only 70-80% will have active viral replication.
  • A viral load test is needed to identify actively infected patients.
  • Like HIV, the antibodies are non-neutralising, i.e. do not control infection.
  • The emphasis in Hepatitis C management is to identify patients so they can be treated with oral direct-acting therapies (DAA).
  • Do not repeat Hepatitis C virus antibody testing in patients with a previous positive Hepatitis C virus (HCV) test. Instead, order Hepatitis C viral load testing for assessment of active versus resolved infection.
  • Do not repeat hepatitis C viral load testing in an individual who has established chronic infection, outside of antiviral treatment.
  • Do not repeat HBV or HCV studies without considering the significance of prior testing 

Interpretation

Negative, Equivocal or Reactive with appropriate comment.

Additional Information